Phillies vs. Cardinals Prediction, Odds, Picks - May 12

Data Skrive

The St. Louis Cardinals and Willson Contreras hit the field at Citizens Bank Park against Bryce Harper and the Philadelphia Phillies on Monday. The Phillies are -176 moneyline favorites in this matchup against the Cardinals (+147). Philadelphia is a 1.5-run favorite (at +119 odds). The contest’s total is set at 8.5 runs.

Here is everything you need to know from a betting perspective on the Phillies-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Phillies vs. Cardinals Game Information & Odds

When: Monday, May 12, 2025 at 6:45 p.m. ET
Where: Citizens Bank Park in Philadelphia, Pennsylvania
How to watch on TV: MLB Network, NBCS-PH, and FDSMW

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Phillies	-176	+147	8.5	-111	-109	-1.5	+119	-142

Phillies vs. Cardinals Prediction

Score Prediction: Phillies 4, Cardinals 3
Total Prediction: Under 8.5 runs
Win Probabilities: Phillies 53%, Cardinals 47%

Phillies vs. Cardinals Betting Insights

This season, the Phillies have been favored 32 times and won 20, or 62.5%, of those games.
Philadelphia has entered 11 games this season favored by -176 or more and is 9-2 in those contests.
The oddsmakers’ moneyline implies a 63.8% chance of a victory for the Phillies.
The Cardinals have been chosen as underdogs in 27 games this year and have walked away with the win 14 times (51.9%) in those games.
St. Louis has yet to win this season when listed as an underdog of +147 or worse on the moneyline this season.
The Cardinals have an implied victory probability of 40.5% according to the moneyline set by oddsmakers for this matchup.